Adopt a wobbly little slime, figure out what it likes to eat, and watch it evolve into new species. Grow your colony, send parties out on quests for gold, staff market stalls that earn while you're away, and fuse your favourites into rarer, mightier forms. No slime ever dies, a neglected one just sulks until you cheer it back up. 
The key bindings can be changed in the settings.